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Chien-Heng Shen Selected Research

p38 Mitogen-Activated Protein Kinases

8/2014Protective effects of Hericium erinaceus mycelium and its isolated erinacine A against ischemia-injury-induced neuronal cell death via the inhibition of iNOS/p38 MAPK and nitrotyrosine.
7/2014Activation of neutral-sphingomyelinase, MAPKs, and p75 NTR-mediating caffeic acid phenethyl ester-induced apoptosis in C6 glioma cells.
6/2014Resistin-induced stromal cell-derived factor-1 expression through Toll-like receptor 4 and activation of p38 MAPK/ NFκB signaling pathway in gastric cancer cells.

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Chien-Heng Shen Research Topics

Disease

11Neoplasms (Cancer)
04/2021 - 03/2012
8Hepatocellular Carcinoma (Hepatoma)
02/2023 - 05/2002
8Colorectal Neoplasms (Colorectal Cancer)
01/2021 - 03/2012
7Infections
01/2024 - 02/2008
5Chronic Hepatitis C
01/2023 - 09/2011
4Stomach Neoplasms (Stomach Cancer)
04/2021 - 06/2014
3Hepatitis C
01/2024 - 01/2020
3Fibrosis (Cirrhosis)
11/2016 - 02/2012
3Liver Cirrhosis (Hepatic Cirrhosis)
01/2016 - 11/2009
3Neoplasm Metastasis (Metastasis)
10/2015 - 03/2012
2Idiopathic Thrombocytopenic Purpura (Thrombocytopenic Purpura, Autoimmune)
11/2021 - 01/2017
2Liver Neoplasms (Liver Cancer)
08/2021 - 01/2021
2Parkinson Disease (Parkinson's Disease)
02/2020 - 03/2016
2Anemia
01/2020 - 10/2013
2Inflammation (Inflammations)
11/2018 - 06/2014
2Colonic Neoplasms (Colon Cancer)
01/2017 - 10/2012
2Brain Injuries (Brain Injury)
03/2016 - 08/2014
2Carcinogenesis
06/2014 - 10/2012
1Body Weight (Weight, Body)
01/2024
1Weight Gain
01/2024
1Hepatitis
02/2023
1Hepatitis B
02/2023
1Hypertension (High Blood Pressure)
01/2023
1Splenomegaly
11/2021
1Leukopenia
11/2021
1Thrombocytopenia (Thrombopenia)
11/2021
1Hepatoblastoma
08/2021
1Chronic Hepatitis B
01/2021
1Hemolytic Anemia
01/2020
1Chronic Renal Insufficiency
01/2020
1Chronic Kidney Failure (Chronic Renal Failure)
11/2018
1Necrosis
01/2017
1Ischemia
08/2014

Drug/Important Bio-Agent (IBA)

5Proteins (Proteins, Gene)FDA Link
05/2022 - 08/2014
4erinacine AIBA
01/2019 - 08/2014
3Antiviral Agents (Antivirals)IBA
01/2024 - 02/2008
3EnzymesIBA
11/2021 - 06/2014
31- (4- (furo(2,3- b)quinolin- 4- ylamino)phenyl)ethanoneIBA
01/2021 - 01/2017
3alpha-Fetoproteins (alpha-Fetoprotein)IBA
11/2018 - 06/2015
3LigandsIBA
04/2018 - 10/2012
3p38 Mitogen-Activated Protein KinasesIBA
08/2014 - 06/2014
2InterferonsIBA
02/2023 - 10/2013
2ailanthoidolIBA
05/2022 - 08/2021
2ImmunosorbentsIBA
11/2021 - 06/2014
2Inosine Triphosphate (ITP)IBA
11/2021 - 01/2017
2CytokinesIBA
08/2021 - 01/2017
2Histones (Histone)IBA
04/2021 - 01/2019
2Proliferating Cell Nuclear Antigen (PCNA)IBA
04/2021 - 01/2021
21- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA
02/2020 - 03/2016
2Hemoglobins (Hemoglobin)IBA
01/2020 - 10/2013
2Ribavirin (Virazole)FDA LinkGeneric
01/2020 - 10/2013
2DiterpenesIBA
03/2016 - 08/2014
2CXC ChemokinesIBA
06/2014 - 10/2012
2Alanine Transaminase (SGPT)IBA
02/2012 - 11/2009
2Aspartate Aminotransferases (Aspartate Transaminase)IBA
02/2012 - 11/2009
1NucleosidesIBA
02/2023
1AlbuminsIBA
01/2023
1Sorafenib (BAY 43-9006)FDA Link
02/2022
1AntibodiesIBA
11/2021
1Platelet Glycoprotein GPIIb-IIIa ComplexIBA
11/2021
1HLA Antigens (Human Leukocyte Antigens)IBA
11/2021
1Transforming Growth Factors (Transforming Growth Factor)IBA
08/2021
1LignansIBA
08/2021
1TNF-Related Apoptosis-Inducing LigandIBA
04/2021
1Cyclin D1IBA
04/2021
1erinacine SIBA
04/2021
1Type I Tumor Necrosis Factor ReceptorsIBA
01/2021
1Tenofovir (Viread)FDA Link
01/2021
1entecavirFDA Link
01/2021
1Fluo-3IBA
01/2021
12',7'-dichlorofluoresceinIBA
01/2021
1isothiocyanic acidIBA
01/2021
1diacetyldichlorofluoresceinIBA
01/2021
1Cyclin B1IBA
01/2021
1Propidium (Propidium Iodide)IBA
01/2021
1AlkaloidsIBA
01/2021
1BromidesIBA
01/2021
1Annexin A5IBA
01/2021
1Fluorescein-5-isothiocyanate (FITC)IBA
01/2021
1Fluorescein (Funduscein)FDA LinkGeneric
01/2021
1glecaprevir and pibrentasvirIBA
11/2020
1SofosbuvirIBA
01/2020
1Phosphotransferases (Kinase)IBA
01/2019
1Fas Ligand Protein (Fas Ligand)IBA
01/2019
1Biomarkers (Surrogate Marker)IBA
01/2018
1AntioxidantsIBA
01/2018
1Interleukin-6 (Interleukin 6)IBA
01/2017
1Thrombopoietin (c-mpl Ligand)IBA
01/2017
1Stem Cell FactorIBA
01/2017
1Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA
01/2017
1InterleukinsIBA
01/2017
1Interleukin-11 (Interleukin 11)IBA
01/2017
1Oxaliplatin (Eloxatin)FDA LinkGeneric
01/2016
12,6- dimethoxy- 1,4,5,8- phenanthrenetetroneIBA
01/2016
13-nitrotyrosineIBA
08/2014
1Nitric Oxide Synthase (NO Synthase)IBA
08/2014
1Reactive Nitrogen SpeciesIBA
08/2014

Therapy/Procedure

10Therapeutics
01/2024 - 02/2008
2Radiofrequency Ablation
11/2018 - 05/2002
1Drug Tapering
01/2020